產品詳情
簡單介紹:
Anti-CD3E+CD3G antibody (1-207) [S3942RM] (STJ11103942)
詳情介紹:
Host: | Rabbit |
Applications: | WB/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-CD3E+CD3G (1-207) is suitable for use in Western Blot and Flow Cytometry research applications. |
Clonality: | Monoclonal |
Clone ID: | S3942RM |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:5000 FC 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunogen Region: | 1-207 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 (CD3E) & 1-182 (CD3G) of human CD3 epsilon&CD3 gamma Heterodimer. |
Immunogen Sequence: | MQSGTHWRVLGLCLLSVGVW GQDGNEEMGGITQTPYKVSI SGTTVILTCPQYPGSEILWQ HNDKNIGGDEDDKNIGSDED HLSLKEFSELEQSGYYVCYP RGSKPEDANFYLYLRARVCE NCMEMDVMSVATIVIVDICI TGGLLLLVYYWSKNRKAKAK PVTRGAGAGGRQRGQNKERP PPVPNPDYEPIRKGQRDLYS GLNQRRI (CD3E) &MEQGKG LAVLILAIILLQGTLAQ |
Background | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma,-delta and-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon,-delta and-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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