Anti-CD3G antibody (Internal) (STJ73095) STJ73095-100|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-CD3G antibody (Internal) (STJ73095)
產品型號：STJ73095-100
產品廠商：ST john's laboratory
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簡單介紹：

Anti-CD3G antibody (Internal) (STJ73095)

詳情介紹：

Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human/Mouse/Rat/Dog/Pig/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-CD3G (Internal) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.3-1µg/ml ELISA-antibody detection limit dilution 1:128000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	CD3G
Gene ID:	917
Uniprot ID:	CD3G_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_000064.1
Immunogen Sequence:	QDGVRQSRASDKQT

Function	Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
Protein Name	T-Cell Surface Glycoprotein Cd3 Gamma Chain T-Cell Receptor T3 Gamma Chain Cd Antigen Cd3g
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-202424 Reactome: R-HSA-202427 Reactome: R-HSA-202430 Reactome: R-HSA-202433 Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-389948 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-9664323 Reactome: R-HSA-9664422
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-T-Cell Surface Glycoprotein Cd3 Gamma Chain antibody Anti-T-Cell Receptor T3 Gamma Chain antibody Anti-Cd Antigen Cd3g antibody Anti-CD3G antibody Anti-T3G antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CD3G antibody (Internal) (STJ73095)