Anti-DPYSL2 antibody (400-500) (STJ116781) STJ116781|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

你添加了1件商品查看購物車

簡單介紹：

Anti-DPYSL2 antibody (400-500) (STJ116781)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DPYSL2 (400-500) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-1:500
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DPYSL2
Gene ID:	1808
Uniprot ID:	DPYL2_HUMAN
Immunogen Region:	400-500
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 400-500 of human CRMP2/CRMP2/DPYSL2 (NP_001377.1).
Immunogen Sequence:	RIAVGSDADLVIWDPDSVKT ISAKTHNSSLEYNIFEGMEC RGSPLVVISQGKIVLEDGTL HVTEGSGRYIPRKPFPDFVY KRIKARSRLAELRGVPRGLY D

Tissue Specificity	Ubiquitous.
Post Translational Modifications	3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509. Phosphorylation at Thr-514 by GSK3B abolishes tubulin-binding leading to destabilization of microtubule assembly in axons and neurodegeneration. Phosphorylation by DYRK2 at Ser-522 is required for subsequent phosphorylation by GSK3B.
Function	Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Protein Name	Dihydropyrimidinase-Related Protein 2 Drp-2 Collapsin Response Mediator Protein 2 Crmp-2 N2a3 Unc-33-Like Phosphoprotein 2 Ulip-2
Database Links	Reactome: R-HSA-399956 Reactome: R-HSA-437239
Cellular Localisation	Cytoplasm Cytosol Cytoskeleton Membrane Tightly But Non-Covalently Associated With Membranes
Alternative Antibody Names	Anti-Dihydropyrimidinase-Related Protein 2 antibody Anti-Drp-2 antibody Anti-Collapsin Response Mediator Protein 2 antibody Anti-Crmp-2 antibody Anti-N2a3 antibody Anti-Unc-33-Like Phosphoprotein 2 antibody Anti-Ulip-2 antibody Anti-DPYSL2 antibody Anti-CRMP2 antibody Anti-ULIP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：Anti-DPYSL2 antibody (400-500) (STJ116781)