產品詳情
簡單介紹：
Anti-DSC1 antibody (749-799 aa) (STJ194228)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Desmocollin-1 (749-799 aa) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSC1 |
| Gene ID: | 1823 |
| Uniprot ID: | DSC1_HUMAN |
| Immunogen Region: | 749-799 aa |
| Specificity: | This antibody detects endogenous levels of DSC1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human DSC1 at the amino acid range 749-799 |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. |
| Protein Name | Desmocollin-1 Cadherin Family Member 1 Desmosomal Glycoprotein 2/3 Dg2/Dg3 |
| Database Links | Reactome: R-HSA-6798695 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Desmosome |
| Alternative Antibody Names | Anti-Desmocollin-1 antibody Anti-Cadherin Family Member 1 antibody Anti-Desmosomal Glycoprotein 2/3 antibody Anti-Dg2/Dg3 antibody Anti-DSC1 antibody Anti-CDHF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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