產品詳情
簡單介紹:
Mouse ITGa3 (Integrin Alpha 3) Sandwich ELISA Kit (STJE0010081)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.118ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This ITGa3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Itga3 |
Gene ID: | 16400 |
Uniprot ID: | ITA3_MOUSE |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Isoform 1 and isoform 2 are expressed in heart and brain. Only isoform 1 is detected in lung. |
Post Translational Modifications | |
Function | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
Protein Name | Integrin Alpha-3 Cd49 Antigen-Like Family Member C Galactoprotein B3 Gapb3 Vla-3 Subunit Alpha Cd Antigen Cd49c Cleaved Into - Integrin Alpha-3 Heavy Chain - Integrin Alpha-3 Light Chain |
Database Links | Reactome: R-MMU-216083 Reactome: -MMU-8874081 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Lipid-Anchor Cell Projection Invadopodium Membrane Filopodium Membrane Enriched Preferentially At Invadopodia Cell Membrane Protrusions That Correspond To Sites Of Cell Invasion In A Collagen-Dependent Manner |
Alternative ELISA Names | Integrin Alpha-3 ELISA kit Cd49 Antigen-Like Family Member C ELISA kit Galactoprotein B3 ELISA kit Gapb3 ELISA kit Vla-3 Subunit Alpha ELISA kit Cd Antigen Cd49c Cleaved Into - Integrin Alpha-3 Heavy Chain - Integrin Alpha-3 Light Chain ELISA kit Itga3 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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