Anti-DUSP16 antibody (416-665) (STJ112194) STJ112194|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DUSP16 antibody (416-665) (STJ112194)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DUSP16 (416-665) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DUSP16
Gene ID:	80824
Uniprot ID:	DUS16_HUMAN
Immunogen Region:	416-665
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 416-665 of human DUSP16 (NP_085143.1).
Immunogen Sequence:	SLHGFSSSEDALEYYKPSTT LDGTNKLCQFSPVQELSEQT PETSPDKEEASIPKKLQTAR PSDSQSKRLHSVRTSSSGTA QRSLLSPLHRSGSVEDNYHT SFLFGLSTSQQHLTKSAGLG LKGWHSDILAPQTSTPSLTS SWYFATESSHFYSASAIYGG SASYSAYSCSQLPTCGDQVY SVRRRQKPSDRADSRRSWHE ESPFEKQFKRRSCQMEFGES IMSENRSREELGKVGSQSS

Post Translational Modifications	Phosphorylated at Ser-446 by MAPK1/ERK2, which prevents its degradation, and thereby stabilizes it and blocks JNK MAPK activity. (Microbial infection) Acetylated at Lys-55 by the M.tuberculosis Eis protein.this leads to the inhibition of JNK-dependent autophagy, phagosome maturation, and ROS (reactive oxygen species) generation for enhanced intracellular survival of M.tuberculosis.
Function	Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Protein Name	Dual Specificity Protein Phosphatase 16 Mitogen-Activated Protein Kinase Phosphatase 7 Map Kinase Phosphatase 7 Mkp-7
Database Links	Reactome: R-HSA-112409 Reactome: R-HSA-5675221 Reactome: R-HSA-9636569 Reactome: R-HSA-9652817
Cellular Localisation	Cytoplasm Nucleus Cytoplasmic Vesicle After Dissociation Upon Agtr Stimulation Re-Associates With Arrb2 On Endocytic Vesicles
Alternative Antibody Names	Anti-Dual Specificity Protein Phosphatase 16 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 7 antibody Anti-Map Kinase Phosphatase 7 antibody Anti-Mkp-7 antibody Anti-DUSP16 antibody Anti-KIAA1700 antibody Anti-MKP7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DUSP16 antibody (416-665) (STJ112194)