Anti-DUSP6 antibody (282-381) [S0MR] (STJ11101230) STJ11101230|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DUSP6 antibody (282-381) [S0MR] (STJ11101230)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-DUSP6 (282-381) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	S0MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DUSP6
Gene ID:	1848
Uniprot ID:	DUS6_HUMAN
Immunogen Region:	282-381
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 282-381 of human DUSP6 (Q16828).
Immunogen Sequence:	ARGKNCGVLVHCLAGISRSV TVTVAYLMQKLNLSMNDAYD IVKMKKSNISPNFNFMGQLL DFERTLGLSSPCDNRVPAQQ LYFTTPSNQNVYQVDSLQST

Tissue Specificity	Expressed in keratinocytes (at protein level).
Function	Inactivates MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain. Promotes cell differentiation by regulating MAPK1/MAPK3 activity and regulating the expression of AP1 transcription factors.
Protein Name	Dual Specificity Protein Phosphatase 6 Dual Specificity Protein Phosphatase Pyst1 Mitogen-Activated Protein Kinase Phosphatase 3 Map Kinase Phosphatase 3 Mkp-3
Database Links	Reactome: R-HSA-112409 Reactome: R-HSA-202670 Reactome: R-HSA-5675221 Reactome: R-HSA-9652817
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Dual Specificity Protein Phosphatase 6 antibody Anti-Dual Specificity Protein Phosphatase Pyst1 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 3 antibody Anti-Map Kinase Phosphatase 3 antibody Anti-Mkp-3 antibody Anti-DUSP6 antibody Anti-MKP3 antibody Anti-PYST1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DUSP6 antibody (282-381) [S0MR] (STJ11101230)