Mouse KLF1 (Kruppel Like Factor 1, Erythroid) Sandwich ELISA Kit Ready-To-Use (STJE0016561) STJE0016561|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse KLF1 (Kruppel Like Factor 1, Erythroid) Sandwich ELISA Kit Ready-To-Use (STJE0016561)
產品型號：STJE0016561
產品廠商：ST john's laboratory
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Mouse KLF1 (Kruppel Like Factor 1, Erythroid) Sandwich ELISA Kit Ready-To-Use (STJE0016561)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	5.8pg/mL
Detection Limit:	15.6-1000pg/mL
Short Description:	This KLF1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Klf1Uniprot ID=KLF1_MOUSE"
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma or other biological fluids.

Tissue Specificity	Erythroid-specific. Only expressed in bone marrow and spleen.
Post Translational Modifications	Acetylated.can be acetylated on both Lys-270 and Lys-288. Acetylation on Lys-270 (by CBP) appears to be the major site affecting EKLF transactivation activity. Sumoylated.sumoylation, promoted by PIAS1, leads to repression of megakaryocyte differentiation. Also promotes the interaction with the CDH4 subunit of the NuRD repression complex. Phosphorylated primarily on serine residues in the transactivation domain. Phosphorylation on Thr-23 is critical for the transactivation activity.
Function	Transcription regulator of erythrocyte development. Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Probably serves as a general switch factor for erythroid development. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
Protein Name	Krueppel-Like Factor 1 Erythroid Krueppel-Like Transcription Factor Eklf
Database Links
Cellular Localisation	Nucleus Colocalizes With Sumo1 In Nuclear Speckles
Alternative ELISA Names	Krueppel-Like Factor 1 ELISA kit Erythroid Krueppel-Like Transcription Factor ELISA kit Eklf ELISA kit Klf1 ELISA kit Elkf ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse KLF1 (Kruppel Like Factor 1, Erythroid) Sandwich ELISA Kit Ready-To-Use (STJE0016561)