Anti-Dysferlin antibody [Ham1/7B6] (STJ16101747) STJ16101747-1|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-Dysferlin antibody [Ham1/7B6] (STJ16101747)
產品型號：STJ16101747-1
產品廠商：ST john's laboratory
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簡單介紹：

Anti-Dysferlin antibody [Ham1/7B6] (STJ16101747)

詳情介紹：

Host:	Mouse
Applications:	IHC-P/IHC-F
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Dysferlin is suitable for use in Immunohistochemistry and Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	Ham1/7B6
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	Lyophilized
Storage Instruction:	Store at 2-8°C upon receipt.

Gene Symbol:	DYSF
Gene ID:	8291
Uniprot ID:	DYSF_HUMAN

Tissue Specificity	Expressed in skeletal muscle, myoblast, myotube and in the syncytiotrophoblast (STB) of the placenta (at protein level). Ubiquitous. Highly expressed in skeletal muscle. Also found in heart, brain, spleen, intestine, placenta and at lower levels in liver, lung, kidney and pancreas.
Function	Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.
Protein Name	Dysferlin Dystrophy-Associated Fer-1-Like Protein Fer-1-Like Protein 1
Database Links	Reactome: R-HSA-445355
Cellular Localisation	Cell Membrane Sarcolemma Single-Pass Type Ii Membrane Protein Cytoplasmic Vesicle Membrane Colocalizes During Muscle Differentiation With Bin1 In The T-Tubule System Of Myotubules And At The Site Of Contact Between Two Myotubes Or A Myoblast And A Myotube Wounding Of Myotubes Led To Its Focal Enrichment To The Site Of Injury And To Its Relocalization In A Ca(2+)-Dependent Manner Toward The Plasma Membrane Colocalizes With Ahnak Ahnak2 And Parvb At The Sarcolemma Of Skeletal Muscle Detected On The Apical Plasma Membrane Of The Syncytiotrophoblast Reaches The Plasmma Membrane Through A Caveolin-Independent Mechanism Retained By Caveolin At The Plasmma Membrane With Cacna1s In The T-Tubule System Of Myotubules Accumulates And Colocalizes With Fusion Vesicles At The Sarcolemma Disruption Sites
Alternative Antibody Names	Anti-Dysferlin antibody Anti-Dystrophy-Associated Fer-1-Like Protein antibody Anti-Fer-1-Like Protein 1 antibody Anti-DYSF antibody Anti-FER1L1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-Dysferlin antibody [Ham1/7B6] (STJ16101747)