Anti-E2F4 antibody (89-198) (STJ11103181) STJ11103181|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-E2F4 antibody (89-198) (STJ11103181)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-E2F4 (89-198) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	E2F4
Gene ID:	1874
Uniprot ID:	E2F4_HUMAN
Immunogen Region:	89-198
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 89-198 of human E2F4 (NP_001941.2).
Immunogen Sequence:	NTREIADKLIELKAEIEELQ QREQELDQHKVWVQQSIRNV TEDVQNSCLAYVTHEDICRC FAGDTLLAIRAPSGTSLEVP IPEGLNGQKKYQIHLKSVSG PIEVLLVNKE

Tissue Specificity	Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Post Translational Modifications	Differentially phosphorylated in vivo.
Function	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Protein Name	Transcription Factor E2f4 E2f-4
Database Links	Reactome: R-HSA-1362277 Reactome: R-HSA-1362300 Reactome: R-HSA-1538133 Reactome: R-HSA-2173796 Reactome: R-HSA-6804114 Reactome: R-HSA-69202 Reactome: R-HSA-69205 Reactome: R-HSA-69231 Reactome: R-HSA-69656
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Transcription Factor E2f4 antibody Anti-E2f-4 antibody Anti-E2F4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-E2F4 antibody (89-198) (STJ11103181)