Anti-ECHS1 antibody (28-290) (STJ111198) STJ111198|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-ECHS1 antibody (28-290) (STJ111198)
產品型號：STJ111198
產品廠商：ST john's laboratory
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Anti-ECHS1 antibody (28-290) (STJ111198)

詳情介紹：

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ECHS1 (28-290) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ECHS1
Gene ID:	1892
Uniprot ID:	ECHM_HUMAN
Immunogen Region:	28-290
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 28-290 of human ECHS1 (NP_004083.3).
Immunogen Sequence:	ASGANFEYIIAEKRGKNNTV GLIQLNRPKALNALCDGLID ELNQALKTFEEDPAVGAIVL TGGDKAFAAGADIKEMQNLS FQDCYSSKFLKHWDHLTQVK KPVIAAVNGYAFGGGCELAM MCDIIYAGEKAQFAQPEILI GTIPGAGGTQRLTRAVGKSL AMEMVLTGDRISAQDAKQAG LVSKICPVETLVEEAIQCAE KIASNSKIVVAMAKESVNAA FEMTLTEGSKLEKKLFYST

Tissue Specificity	Liver, fibroblast, muscle. Barely detectable in spleen and kidney.
Function	Converts unsaturated trans-2-enoyl-CoA species ((2E)-enoyl-CoA) to the corresponding (3S)-3hydroxyacyl-CoA species through addition of a water molecule to the double bond. Catalyzes the hydration of medium- and short-chained fatty enoyl-CoA thioesters from 4 carbons long (C4) up to C16. Has high substrate specificity for crotonyl-CoA ((2E)-butenoyl-CoA) and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA) and methacrylyl-CoA ((2E)-2-methylpropenoyl-CoA). Can bind tiglyl-CoA (2-methylcrotonoyl-CoA), but hydrates only a small amount of this substrate. Plays a key role in the beta-oxidation spiral of short- and medium-chain fatty acid oxidation. At a lower rate than the hydratase reaction, catalyzes the isomerase reaction of trans-3-enoyl-CoA species (such as (3E)-hexenoyl-CoA) to trans-2-enoyl-CoA species (such as (2E)-hexenoyl-CoA), which are subsequently hydrated to 3(S)-3-hydroxyacyl-CoA species (such as (3S)-hydroxyhexanoyl-CoA).
Protein Name	Enoyl-Coa Hydratase - Mitochondrial Mech Mech1 Enoyl-Coa Hydratase 1 Echs1 Short-Chain Enoyl-Coa Hydratase Sceh
Database Links	Reactome: R-HSA-70895 Reactome: R-HSA-77310 Reactome: R-HSA-77346 Reactome: R-HSA-77348 Reactome: R-HSA-77350 Reactome: R-HSA-77352
Cellular Localisation	Mitochondrion Matrix
Alternative Antibody Names	Anti-Enoyl-Coa Hydratase - Mitochondrial antibody Anti-Mech antibody Anti-Mech1 antibody Anti-Enoyl-Coa Hydratase 1 antibody Anti-Echs1 antibody Anti-Short-Chain Enoyl-Coa Hydratase antibody Anti-Sceh antibody Anti-ECHS1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ECHS1 antibody (28-290) (STJ111198)