Anti-EFEMP2 antibody (91-140 aa) (STJ93074) STJ93074|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-EFEMP2 antibody (91-140 aa) (STJ93074)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-EGF-containing fibulin-like extracellular matrix protein 2 (91-140 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	EFEMP2
Gene ID:	30008
Uniprot ID:	FBLN4_HUMAN
Immunogen Region:	91-140 aa
Specificity:	Fibulin-4 Polyclonal Antibody detects endogenous levels of Fibulin-4 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human EFEMP2 at the amino acid range 91-140

Function	Plays a crucial role in elastic fiber formation in tissue, and in the formation of ultrastructural connections between elastic laminae and smooth muscle cells in the aorta, therefore participates in terminal differentiation and maturation of smooth muscle cell (SMC) and in the mechanical properties and wall integrity maintenance of the aorta. In addition, is involved in the control of collagen fibril assembly in tissue throught proteolytic activation of LOX leading to cross- linking of collagen and elastin. Also promotes ELN coacervation and participates in the deposition of ELN coacervates on to microfibrils but also regulates ELN cross- linking through LOX interaction. Moreover adheres to the cells through heparin binding in a calcium-dependent manner and regulates vascularlar smooth muscle cells proliferation through angiotensin signaling.
Protein Name	Egf-Containing Fibulin-Like Extracellular Matrix Protein 2 Fibulin-4 Fibl-4 Protein Uph1
Database Links	Reactome: R-HSA-2129379
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Basement Membrane Localizes On The Microfibrils Surrounding Eln Cores
Alternative Antibody Names	Anti-Egf-Containing Fibulin-Like Extracellular Matrix Protein 2 antibody Anti-Fibulin-4 antibody Anti-Fibl-4 antibody Anti-Protein Uph1 antibody Anti-EFEMP2 antibody Anti-FBLN4 antibody Anti-UNQ200 antibody Anti-PRO226 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-EFEMP2 antibody (91-140 aa) (STJ93074)