Mouse PIGR (Polymeric Immunoglobulin Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017845) STJE0017845|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse PIGR (Polymeric Immunoglobulin Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017845)
產品型號：STJE0017845
產品廠商：ST john's laboratory
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簡單介紹：

Mouse PIGR (Polymeric Immunoglobulin Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017845)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	1.34ng/mL
Detection Limit:	3.12-200ng/mL
Short Description:	This PIGR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Pigr
Gene ID:	18703
Uniprot ID:	PIGR_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	N-glycosylated. N-glycosylation is required for anchoring IgA molecules to mucus, but is not necessary for Ig binding.
Function	Polymeric immunoglobulin receptor: Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. Secretory component: Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens. On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
Protein Name	Polymeric Immunoglobulin Receptor Pigr Poly-Ig Receptor Cleaved Into - Secretory Component
Database Links	Reactome: R-MMU-6798695
Cellular Localisation	Polymeric Immunoglobulin Receptor: Cell Membrane Single-Pass Type I Membrane Protein Secretory Component: Secreted
Alternative ELISA Names	Polymeric Immunoglobulin Receptor ELISA kit Pigr ELISA kit Poly-Ig Receptor Cleaved Into - Secretory Component ELISA kit Pigr ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse PIGR (Polymeric Immunoglobulin Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017845)