產品詳情
簡單介紹:
Anti-EPCAM antibody [7E11] (STJ98021)
詳情介紹:
Host: | Mouse |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Epithelial cell adhesion molecule is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Monoclonal |
Clone ID: | 7E11 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC 1:200-1:1000 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EPCAM |
Gene ID: | 4072 |
Uniprot ID: | EPCAM_HUMAN |
Specificity: | EP-CAM Monoclonal Antibody detects endogenous levels of EP-CAM protein. |
Immunogen: | Purified recombinant fragment of human EP-CAM expressed in E. Coli. |
Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
Protein Name | Epithelial Cell Adhesion Molecule Ep-Cam Adenocarcinoma-Associated Antigen Cell Surface Glycoprotein Trop-1 Epithelial Cell Surface Antigen Epithelial Glycoprotein Egp Epithelial Glycoprotein 314 Egp314 Hegp314 Ks 1/4 Antigen Ksa Major Gastrointestinal Tumor-Associated Protein Ga733-2 Tumor-Associated Calcium Signal Transducer 1 Cd Antigen Cd326 |
Database Links | Reactome: R-HSA-202733 |
Cellular Localisation | Lateral Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Tight Junction Colocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
Alternative Antibody Names | Anti-Epithelial Cell Adhesion Molecule antibody Anti-Ep-Cam antibody Anti-Adenocarcinoma-Associated Antigen antibody Anti-Cell Surface Glycoprotein Trop-1 antibody Anti-Epithelial Cell Surface Antigen antibody Anti-Epithelial Glycoprotein antibody Anti-Egp antibody Anti-Epithelial Glycoprotein 314 antibody Anti-Egp314 antibody Anti-Hegp314 antibody Anti-Ks 1/4 Antigen antibody Anti-Ksa antibody Anti-Major Gastrointestinal Tumor-Associated Protein Ga733-2 antibody Anti-Tumor-Associated Calcium Signal Transducer 1 antibody Anti-Cd Antigen Cd326 antibody Anti-EPCAM antibody Anti-GA733-2 antibody Anti-M1S2 antibody Anti-M4S1 antibody Anti-MIC18 antibody Anti-TACSTD1 antibody Anti-TROP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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