Anti-EPHB4 antibody (900-984) {FITC} (STJ500941) STJ500941-100|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-EPHB4 antibody (900-984) {FITC} (STJ500941)
產品型號：STJ500941-100
產品廠商：ST john's laboratory
產品文檔：

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簡單介紹：

Anti-EPHB4 antibody (900-984) {FITC} (STJ500941)

詳情介紹：

Host:	Rabbit
Applications:	ELISA/WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-EPHB4 (900-984) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	FITC
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.55-0.62 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	EPHB4
Gene ID:	2050
Uniprot ID:	EPHB4_HUMAN
Immunogen Region:	900-984
Immunogen:	Synthetic peptide taken within amino acid region 900-984 on human Ephrin B4 receptor protein.

Tissue Specificity	Abundantly expressed in placenta but also detected in kidney, liver, lung, pancreas, skeletal muscle and heart. Expressed in primitive and myeloid, but not lymphoid, hematopoietic cells. Also observed in cell lines derived from liver, breast, colon, lung, melanocyte and cervix.
Post Translational Modifications	Phosphorylated.autophosphorylation is stimulated by EFNB2.
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.
Protein Name	Ephrin Type-B Receptor 4 Hepatoma Transmembrane Kinase Tyrosine-Protein Kinase Tyro11
Database Links	Reactome: R-HSA-2682334 Reactome: R-HSA-3928662 Reactome: R-HSA-3928664 Reactome: R-HSA-3928665
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Ephrin Type-B Receptor 4 antibody Anti-Hepatoma Transmembrane Kinase antibody Anti-Tyrosine-Protein Kinase Tyro11 antibody Anti-EPHB4 antibody Anti-HTK antibody Anti-MYK1 antibody Anti-TYRO11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-EPHB4 antibody (900-984) {FITC} (STJ500941)