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Anti-EPHB4 antibody [5B5] (STJ98036) STJ98036|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：Anti-EPHB4 antibody [5B5] (STJ98036)

  • 產品型號：STJ98036
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
Anti-EPHB4 antibody [5B5] (STJ98036)
詳情介紹：
Host: Mouse
Applications: WB/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Ephrin type-B receptor 4 is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 5B5
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EPHB4
Gene ID: 2050
Uniprot ID: EPHB4_HUMAN
Specificity: EphB4 Monoclonal Antibody detects endogenous levels of EphB4 protein.
Immunogen: Purified recombinant extracellular fragment of human EphB4 fused with hIgGFc tag expressed in HEK293 cell line.
Post Translational Modifications Phosphorylated.autophosphorylation is stimulated by EFNB2.
Function Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.
Protein Name Ephrin Type-B Receptor 4
Hepatoma Transmembrane Kinase
Tyrosine-Protein Kinase Tyro11
Database Links Reactome: R-HSA-2682334
Reactome: R-HSA-3928662
Reactome: R-HSA-3928664
Reactome: R-HSA-3928665
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Ephrin Type-B Receptor 4 antibody
Anti-Hepatoma Transmembrane Kinase antibody
Anti-Tyrosine-Protein Kinase Tyro11 antibody
Anti-EPHB4 antibody
Anti-HTK antibody
Anti-MYK1 antibody
Anti-TYRO11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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