產品詳情
簡單介紹：
Anti-EPN1 antibody (140-220 aa) (STJ92966)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Epsin-1 (140-220 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EPN1 |
| Gene ID: | 29924 |
| Uniprot ID: | EPN1_HUMAN |
| Immunogen Region: | 140-220 aa |
| Specificity: | Epsin 1 Polyclonal Antibody detects endogenous levels of Epsin 1 protein. |
| Immunogen: | Synthesized peptide derived from Epsin 1 at the amino acid range 140-220 |
| Function | Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. |
| Protein Name | Epsin-1 Eh Domain-Binding Mitotic Phosphoprotein Eps-15-Interacting Protein 1 |
| Database Links | Reactome: R-HSA-182971 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
| Cellular Localisation | Cytoplasm Cell Membrane Peripheral Membrane Protein Nucleus Membrane Clathrin-Coated Pit Associated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are Forming Colocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma Membrane Detected In Presynaptic Nerve Terminals And In Golgi Stacks May Shuttle To The Nucleus When Associated With Zbtb16/Znf145 |
| Alternative Antibody Names | Anti-Epsin-1 antibody Anti-Eh Domain-Binding Mitotic Phosphoprotein antibody Anti-Eps-15-Interacting Protein 1 antibody Anti-EPN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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