Mouse RSPO3 (R-Spondin 3) Sandwich ELISA Kit Ready-To-Use (STJE0018338) STJE0018338|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

產品名稱：Mouse RSPO3 (R-Spondin 3) Sandwich ELISA Kit Ready-To-Use (STJE0018338)
產品型號：STJE0018338
產品廠商：ST john's laboratory
產品文檔：

你添加了1件商品查看購物車

簡單介紹：

Mouse RSPO3 (R-Spondin 3) Sandwich ELISA Kit Ready-To-Use (STJE0018338)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.061ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This RSPO3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Rspo3
Gene ID:	72780
Uniprot ID:	RSPO3_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Highly expressed in endothelial cells.
Post Translational Modifications
Function	Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Acts as a key regulator of angiogenesis by controlling vascular stability and pruning: acts by activating the non-canonical Wnt signaling pathway in endothelial cells. Can also amplify Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3.
Protein Name	R-Spondin-3 Cabriolet Cysteine-Rich And Single Thrombospondin Domain-Containing Protein 1 Cristin-1 Nucleopondin Roof Plate-Specific Spondin-3
Database Links	Reactome: R-MMU-4641263
Cellular Localisation	Secreted
Alternative ELISA Names	R-Spondin-3 ELISA kit Cabriolet ELISA kit Cysteine-Rich And Single Thrombospondin Domain-Containing Protein 1 ELISA kit Cristin-1 ELISA kit Nucleopondin ELISA kit Roof Plate-Specific Spondin-3 ELISA kit Rspo3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：Mouse RSPO3 (R-Spondin 3) Sandwich ELISA Kit Ready-To-Use (STJE0018338)