Anti-ERCC6L antibody (300-400) (STJ27892) STJ27892|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

所在位置: 首頁> 產品目錄> S類> ST john's laboratory>

查看大圖

產品名稱：Anti-ERCC6L antibody (300-400) (STJ27892)
產品型號：STJ27892
產品廠商：ST john's laboratory
產品文檔：

你添加了1件商品查看購物車

簡單介紹：

Anti-ERCC6L antibody (300-400) (STJ27892)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ERCC6L (300-400) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ERCC6L
Gene ID:	54821
Uniprot ID:	ERC6L_HUMAN
Immunogen Region:	300-400
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ERCC6L (NP_060139.2).
Immunogen Sequence:	KDATPGEKALGFKISENLMA IIKPYFLRRTKEDVQKKKSS NPEARLNEKNPDVDAICEMP SLSRKNDLIIWIRLVPLQEE IYRKFVSLDHIKELLMETRS P

Post Translational Modifications	Phosphorylation by PLK1 prevents the association with chromosome arms and restricts its localization to the kinetochore-centromere region.
Function	DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. Functions as ATP-dependent DNA translocase. Can promote Holliday junction branch migration (in vitro).
Protein Name	Dna Excision Repair Protein Ercc-6-Like Atp-Dependent Helicase Ercc6-Like Plk1-Interacting Checkpoint Helicase Tumor Antigen Bj-Hcc-15
Database Links	Reactome: R-HSA-141444 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-5663220 Reactome: R-HSA-68877 Reactome: R-HSA-9648025
Cellular Localisation	Chromosome Centromere Kinetochore Localizes To Kinetochores Inner Centromeres And Thin Threads Connecting Separating Chromosomes Even During Anaphase In Prometaphase Cells It Mostly Concentrates In Between Kinetochores In Metaphase It Localizes To Numerous Thin Threads That Stretch Between Sister Kinetochores Of The Aligned Chromosomes And Are Composed Of Catenated Centromeric Dna Evolution From Inner Centromeres To Thin Threads Takes Place In Response To Tension Resolution Of Thin Threads Requires Topoisomerase 2-Alpha (Top2a) After Anaphase Onset
Alternative Antibody Names	Anti-Dna Excision Repair Protein Ercc-6-Like antibody Anti-Atp-Dependent Helicase Ercc6-Like antibody Anti-Plk1-Interacting Checkpoint Helicase antibody Anti-Tumor Antigen Bj-Hcc-15 antibody Anti-ERCC6L antibody Anti-PICH antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

姓名：

電話：

您的需求：

產品名稱：Anti-ERCC6L antibody (300-400) (STJ27892)