產品詳情
簡單介紹：
Anti-ESA antibody [MOC‐31] (STJ180098)
詳情介紹：
| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-ESA is suitable for use in Immunohistochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | MOC‐31 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% proclin<="" td=""> |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | FLOT2 |
| Gene ID: | 2319 |
| Uniprot ID: | FLOT2_HUMAN |
| Specificity: | Positive control: Colon carcinoma |
| Immunogen: | Neuraminidase treated GLS-1 human small cell lung carcinoma cells |
| Tissue Specificity | In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes. |
| Post Translational Modifications | ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells. |
| Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function. |
| Protein Name | Flotillin-2 Epidermal Surface Antigen Esa Membrane Component Chromosome 17 Surface Marker 1 |
| Database Links | Reactome: R-HSA-5213460 Reactome: R-HSA-5675482 Reactome: R-HSA-8849932 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9696264 Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell Membrane Peripheral Membrane Protein Membrane Caveola Endosome Lipid-Anchor Membrane-Associated Protein Of Caveolae |
| Alternative Antibody Names | Anti-Flotillin-2 antibody Anti-Epidermal Surface Antigen antibody Anti-Esa antibody Anti-Membrane Component Chromosome 17 Surface Marker 1 antibody Anti-FLOT2 antibody Anti-ESA1 antibody Anti-M17S1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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