Mouse TLR1 (Toll Like Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0019015) STJE0019015|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse TLR1 (Toll Like Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0019015)
產品型號：STJE0019015
產品廠商：ST john's laboratory
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簡單介紹：

Mouse TLR1 (Toll Like Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0019015)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.108ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This TLR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Tlr1
Gene ID:	21897
Uniprot ID:	TLR1_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for M.tuberculosis lipoproteins LprG, LpqH and PhoS1 (pstS1), in conjunction with TLR2 and for some but not all lipoproteins CD14 and/or CD36. The lipoproteins act as agonists to modulate antigen presenting cell functions in response to the pathogen.
Protein Name	Toll-Like Receptor 1 Toll/Interleukin-1 Receptor-Like Protein Til Cd Antigen Cd281
Database Links	Reactome: R-MMU-1461957 Reactome: -MMU-5686938
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Cytoplasmic Vesicle Phagosome Membrane Membrane Raft Golgi Apparatus Does Not Reside In Lipid Rafts Before Stimulation But Accumulates Increasingly In The Raft Upon The Presence Of The Microbial Ligand In Response To Triacylated Lipoproteins Tlr2:Tlr1 Heterodimers Are Recruited In Lipid Rafts This Recruitment Determine The Intracellular Targeting To The Golgi Apparatus
Alternative ELISA Names	Toll-Like Receptor 1 ELISA kit Toll/Interleukin-1 Receptor-Like Protein ELISA kit Til ELISA kit Cd Antigen Cd281 ELISA kit Tlr1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse TLR1 (Toll Like Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0019015)