Anti-CDCP1-Isoform 1 antibody (C-Term) (STJ70098) STJ70098-100|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-CDCP1-Isoform 1 antibody (C-Term) (STJ70098)
產品型號：STJ70098-100
產品廠商：ST john's laboratory
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簡單介紹：

Anti-CDCP1-Isoform 1 antibody (C-Term) (STJ70098)

詳情介紹：

Host:	Goat
Applications:	Pep-ELISA/WB/IHC
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-CDCP1-Isoform 1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-1-3µg/ml IHC-5µg/ml ELISA-antibody detection limit dilution 1:32000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	CDCP1
Gene ID:	64866
Uniprot ID:	CDCP1_HUMAN
Immunogen Region:	C-Term
Accession Number:	NP_073753.3
Specificity:	This antibody is expected to recognize isoform 1 (NP_073753.3) only.
Immunogen Sequence:	PLLNTQEPMEPAE

Post Translational Modifications	Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5. N-glycosylated. A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.
Function	May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Protein Name	Cub Domain-Containing Protein 1 Membrane Glycoprotein Gp140 Subtractive Immunization M Plus Hep3-Associated 135 Kda Protein Sima135 Transmembrane And Associated With Src Kinases Cd Antigen Cd318
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Membrane Protein Shedding May Also Lead To A Soluble Peptide Isoform 3: Secreted
Alternative Antibody Names	Anti-Cub Domain-Containing Protein 1 antibody Anti-Membrane Glycoprotein Gp140 antibody Anti-Subtractive Immunization M Plus Hep3-Associated 135 Kda Protein antibody Anti-Sima135 antibody Anti-Transmembrane And Associated With Src Kinases antibody Anti-Cd Antigen Cd318 antibody Anti-CDCP1 antibody Anti-TRASK antibody Anti-UNQ2486 antibody Anti-PRO5773 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CDCP1-Isoform 1 antibody (C-Term) (STJ70098)