產品詳情
簡單介紹:
Mouse ZP2 (Zona Pellucida Glycoprotein 2, Sperm Receptor) Sandwich ELISA Kit (STJE0013149)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.061ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This ZP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Zp2 |
Gene ID: | 22787 |
Uniprot ID: | ZP2_MOUSE |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in oocytes (at protein level). |
Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. Proteolytically cleaved in the N-terminal part by the metalloendopeptidase ASTL exocytosed from cortical granules after fertilization, yielding a N-terminal peptide of about 30 kDa which remains covalently attached to the C-terminal peptide via disulfide bond(s). This cleavage may play an important role in the post-fertilization block to polyspermy. Additional proteolytically cleavage of the N-terminal peptide of 30 kDa occurs in one-cell and two-cell embryos. N-glycosylated. O-glycosylated.contains sulfate-substituted glycans. |
Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. |
Protein Name | Zona Pellucida Sperm-Binding Protein 2 Zona Pellucida Glycoprotein 2 Zp-2 Zona Pellucida Protein A Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 2 |
Database Links | Reactome: R-MMU-2534343 |
Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 2: Zona Pellucida Cell Membrane Single-Pass Type I Membrane Protein |
Alternative ELISA Names | Zona Pellucida Sperm-Binding Protein 2 ELISA kit Zona Pellucida Glycoprotein 2 ELISA kit Zp-2 ELISA kit Zona Pellucida Protein A Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 2 ELISA kit Zp2 ELISA kit Zp-2 ELISA kit Zpa ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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