產品詳情
簡單介紹:
Anti-FCER2 antibody (222-321) [S0MR] (STJ11101330)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-CD23 (222-321) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Monoclonal |
Clone ID: | S0MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FCER2 |
Gene ID: | 2208 |
Uniprot ID: | FCER2_HUMAN |
Immunogen Region: | 222-321 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 222-321 of human CD23 (P06734). |
Immunogen Sequence: | GLRNLDLKGEFIWVDGSHVD YSNWAPGEPTSRSQGEDCVM MRGSGRWNDAFCDRKLGAWV CDRLATCTPPASEGSAESMG PDSRPDPDGRLPTPSAPLHS |
Post Translational Modifications | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. |
Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
Protein Name | Low Affinity Immunoglobulin Epsilon Fc Receptor Blast-2 C-Type Lectin Domain Family 4 Member J Fc-Epsilon-Rii Immunoglobulin E-Binding Factor Lymphocyte Ige Receptor Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form |
Database Links | Reactome: R-HSA-2197563 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Lipid-Anchor Secreted Also Exists As A Soluble Excreted Form Scd23 |
Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody Anti-Blast-2 antibody Anti-C-Type Lectin Domain Family 4 Member J antibody Anti-Fc-Epsilon-Rii antibody Anti-Immunoglobulin E-Binding Factor antibody Anti-Lymphocyte Ige Receptor antibody Anti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody Anti-FCER2 antibody Anti-CD23A antibody Anti-CLEC4J antibody Anti-FCE2 antibody Anti-IGEBF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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