產品詳情
簡單介紹:
Anti-FCGR3B antibody (90-170 aa) (STJ192518)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor III-B (90-170 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FCGR3B |
Gene ID: | 2215 |
Uniprot ID: | FCG3B_HUMAN |
Immunogen Region: | 90-170 aa |
Specificity: | FCG3B Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
Post Translational Modifications | Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage. |
Function | Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. |
Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B Fc-Gamma Riii-Beta Cd16-I Fc-Gamma Riii Fc-Gamma Riiib Fcriii Fcriiib Fcr-10 Igg Fc Receptor Iii-1 Cd Antigen Cd16b |
Database Links | Reactome: R-HSA-163125 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Secreted After Cleavage |
Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B antibody Anti-Fc-Gamma Riii-Beta antibody Anti-Cd16-I antibody Anti-Fc-Gamma Riii antibody Anti-Fc-Gamma Riiib antibody Anti-Fcriii antibody Anti-Fcriiib antibody Anti-Fcr-10 antibody Anti-Igg Fc Receptor Iii-1 antibody Anti-Cd Antigen Cd16b antibody Anti-FCGR3B antibody Anti-CD16B antibody Anti-FCG3 antibody Anti-FCGR3 antibody Anti-IGFR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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