產品詳情
簡單介紹:
Anti-CDH23 antibody (61-110 aa) (STJ91964)
詳情介紹:
Host: | Rabbit |
Applications: | IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Cadherin-23 (61-110 aa) is suitable for use in Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IF 1:200-1:1000 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CDH23 |
Gene ID: | 64072 |
Uniprot ID: | CAD23_HUMAN |
Immunogen Region: | 61-110 aa |
Specificity: | Cadherin-23 Polyclonal Antibody detects endogenous levels of Cadherin-23 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human CDH23 at the amino acid range 61-110 |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. |
Protein Name | Cadherin-23 Otocadherin |
Database Links | Reactome: R-HSA-9662360 Reactome: R-HSA-9662361 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Cadherin-23 antibody Anti-Otocadherin antibody Anti-CDH23 antibody Anti-KIAA1774 antibody Anti-KIAA1812 antibody Anti-UNQ1894 antibody Anti-PRO4340 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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