產品詳情
簡單介紹：
Anti-CDH23/USH1D antibody (Internal) (STJ71691)
詳情介紹：
| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-CDH23/USH1D (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | WB-1-3µg/ml ELISA-antibody detection limit dilution 1:1000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CDH23 |
| Gene ID: | 64072 |
| Uniprot ID: | CAD23_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_071407.3; NP_443068.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_071407.3; NP_443068.1). |
| Immunogen Sequence: | YNISLYENVTVGTS |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. |
| Protein Name | Cadherin-23 Otocadherin |
| Database Links | Reactome: R-HSA-9662360 Reactome: R-HSA-9662361 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-23 antibody Anti-Otocadherin antibody Anti-CDH23 antibody Anti-KIAA1774 antibody Anti-KIAA1812 antibody Anti-UNQ1894 antibody Anti-PRO4340 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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