Anti-FGD5 antibody (1000-1200) (STJ117406) STJ117406|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-FGD5 antibody (1000-1200) (STJ117406)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FGD5 (1000-1200) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FGD5
Gene ID:	152273
Uniprot ID:	FGD5_HUMAN
Immunogen Region:	1000-1200
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human FGD5 (NP_689749.3).
Immunogen Sequence:	YLGLLSENCLHSPRLAAAVR EFEQSVQGGSQTAKHRLLRV VQRLFQYQVLLTDYLNNLCP DSAEYDNTQGALSLISKVTD RANDSMEQGENLQKLVHIEH SVRGQGDLLQPGREFLKEGT LMKVTGKNRRPRHLFLMNDV LLYTYPQKDGKYRLKNTLAV ANMKVSRPVMEKVPYALKIE TSESCLMLSASSCAERDEWY G

Tissue Specificity	Expressed in endothelial cells (at protein level).
Function	Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Protein Name	Fyve - Rhogef And Ph Domain-Containing Protein 5 Zinc Finger Fyve Domain-Containing Protein 23
Database Links	Reactome: R-HSA-9013149
Cellular Localisation	Cytoplasm Cytoskeleton Cell Projection Ruffle Membrane Endoplasmic Reticulum Golgi Apparatus Early Endosome In Peripheral Membrane Ruffles Colocolizes With F-Actin In Confluent Huvecs Detected At Cell-Cell-Contact Sites Where It Colocalizes With Vascular Endothelial Cadherin/Cdh5
Alternative Antibody Names	Anti-Fyve - Rhogef And Ph Domain-Containing Protein 5 antibody Anti-Zinc Finger Fyve Domain-Containing Protein 23 antibody Anti-FGD5 antibody Anti-ZFYVE23 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-FGD5 antibody (1000-1200) (STJ117406)