產品詳情
簡單介紹:
Anti-CDK16 antibody (277-496) (STJ117850)
詳情介紹:
Host: | Rabbit |
Applications: | IF |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CDK16 (277-496) is suitable for use in Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CDK16 |
Gene ID: | 5127 |
Uniprot ID: | CDK16_HUMAN |
Immunogen Region: | 277-496 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-496 of human CDK16 (NP_006192.1). |
Immunogen Sequence: | CHRQKVLHRDLKPQNLLINE RGELKLADFGLARAKSIPTK TYSNEVVTLWYRPPDILLGS TDYSTQIDMWGVGCIFYEMA TGRPLFPGSTVEEQLHFIFR ILGTPTEETWPGILSNEEFK TYNYPKYRAEALLSHAPRLD SDGADLLTKLLQFEGRNRIS AEDAMKHPFFLSLGERIHKL PDTTSIFALKEIQLQKEASL RSSSMPDSGRPAFRVVDTEF |
Tissue Specificity | Detected in pancreas islets (at protein level). Detected in brain and pancreas. |
Post Translational Modifications | Phosphorylation at Ser-153 inhibits kinase activity. |
Function | Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development. Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro). |
Protein Name | Cyclin-Dependent Kinase 16 Cell Division Protein Kinase 16 Pctaire-Motif Protein Kinase 1 Serine/Threonine-Protein Kinase Pctaire-1 |
Cellular Localisation | Cytoplasm Cytoplasmic Vesicle Secretory Vesicle Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Synapse Synaptosome Colocalizes With Insulin In Pancreas Islets Recruited To The Cell Membrane By Ccny |
Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 16 antibody Anti-Cell Division Protein Kinase 16 antibody Anti-Pctaire-Motif Protein Kinase 1 antibody Anti-Serine/Threonine-Protein Kinase Pctaire-1 antibody Anti-CDK16 antibody Anti-PCTAIRE1 antibody Anti-PCTK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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