產品詳情
簡單介紹：
Anti-FGF21 antibody (29-209) [S7MR] (STJ11101967)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-FGF21 (29-209) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:5000 IHC-P 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FGF21 |
| Gene ID: | 26291 |
| Uniprot ID: | FGF21_HUMAN |
| Immunogen Region: | 29-209 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-209 of human FGF21 (NP_061986.1). |
| Immunogen Sequence: | HPIPDSSPLLQFGGQVRQRY LYTDDAQQTEAHLEIREDGT VGGAADQSPESLLQLKALKP GVIQILGVKTSRFLCQRPDG ALYGSLHFDPEACSFRELLL EDGYNVYQSEAHGLPLHLPG NKSPHRDPAPRGPARFLPLP GLPPALPEPPGILAPQPPDV GSSDPLSMVGPSQGRSPSYA S |
| Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. |
| Protein Name | Fibroblast Growth Factor 21 Fgf-21 |
| Database Links | Reactome: R-HSA-189200 Reactome: R-HSA-8963889 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 21 antibody Anti-Fgf-21 antibody Anti-FGF21 antibody Anti-UNQ3115 antibody Anti-PRO10196 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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