產品詳情
簡單介紹：
Anti-FIP1L1 antibody (1-300) (STJ29218)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FIP1L1 (1-300) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FIP1L1 |
| Gene ID: | 81608 |
| Uniprot ID: | FIP1_HUMAN |
| Immunogen Region: | 1-300 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human FIP1L1 (NP_001128409.1). |
| Immunogen Sequence: | MSAGEVERLVSELSGGTGGD EEEEWLYGDENEVERPEEEN ASANPPSGIEDETAENGVPK PKVTETEDDSDSDSDDDEDD VHVTIGDIKTGAPQYGSYGT APVNLNIKTGGRVYGTTGTK VKGVDLDAPGSINGVPLLEV DLDSFEDKPWRKPGADLSDY FNYGFNEDTWKAYCEKQKRI RMGLEVIPVTSTTNKITAED CTMEVTPGAEIQDGRFNLFK VQQGRTGNSEKETALPSTK |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex. |
| Protein Name | Pre-Mrna 3'-End-Processing Factor Fip1 Hfip1 Fip1-Like 1 Protein Factor Interacting With Pap Rearranged In Hypereosinophilia |
| Database Links | Reactome: R-HSA-159231 Reactome: R-HSA-72187 Reactome: R-HSA-72203 Reactome: R-HSA-73856 Reactome: R-HSA-77595 Reactome: R-HSA-9673766 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pre-Mrna 3'-End-Processing Factor Fip1 antibody Anti-Hfip1 antibody Anti-Fip1-Like 1 Protein antibody Anti-Factor Interacting With Pap antibody Anti-Rearranged In Hypereosinophilia antibody Anti-FIP1L1 antibody Anti-FIP1 antibody Anti-RHE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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