產品詳情
簡單介紹:
Anti-CDX1 antibody (136-265) (STJ28280)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CDX1 (136-265) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CDX1 |
Gene ID: | 1044 |
Uniprot ID: | CDX1_HUMAN |
Immunogen Region: | 136-265 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 136-265 of human CDX1 (NP_001795.2). |
Immunogen Sequence: | MRRSVAAGGGGGSGKTRTKD KYRVVYTDHQRLELEKEFHY SRYITIRRKSELAANLGLTE RQVKIWFQNRRAKERKVNKK KQQQQQPPQPPMAHDITATP AGPSLGGLCPSNTSLLATSS PMPVKEEFLP |
Tissue Specificity | Intestinal epithelium. |
Function | Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA. |
Protein Name | Homeobox Protein Cdx-1 Caudal-Type Homeobox Protein 1 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Homeobox Protein Cdx-1 antibody Anti-Caudal-Type Homeobox Protein 1 antibody Anti-CDX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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