產品詳情
簡單介紹：
Anti-FPR1 antibody (250-350) (STJ11103976)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Fmet-Leu-Phe Receptor (250-350) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FPR1 |
| Gene ID: | 2357 |
| Uniprot ID: | FPR1_HUMAN |
| Immunogen Region: | 250-350 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human FPR1 (NP_002020.1). |
| Immunogen Sequence: | FFLCWSPYQVVALIATVRIR ELLQGMYKEIGIAVDVTSAL AFFNSCLNPMLYVFMGQDFR ERLIHALPASLERALTEDST QTSDTATNSTLPSAEVELQA K |
| Tissue Specificity | Neutrophils. |
| Post Translational Modifications | Phosphorylated.which is necessary for desensitization. |
| Function | High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis. |
| Protein Name | Fmet-Leu-Phe Receptor Fmlp Receptor N-Formyl Peptide Receptor Fpr N-Formylpeptide Chemoattractant Receptor |
| Database Links | Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6783783 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Internalizes In Presence Of Its Ligands Fmlp Tafa4 And Ctsg |
| Alternative Antibody Names | Anti-Fmet-Leu-Phe Receptor antibody Anti-Fmlp Receptor antibody Anti-N-Formyl Peptide Receptor antibody Anti-Fpr antibody Anti-N-Formylpeptide Chemoattractant Receptor antibody Anti-FPR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
相關信息
![Anti-14-3-3 beta/Theta antibody (1-100) [S1MR] (STJ11103651)](http://y1.yzimgs.com/uploads/465546/2024520-20551366.png?imageView2/2/w/200/h/200)
- 細胞培養玄學-MRC-5細胞 2025-01-07
- Ocean NanoTech定製的詳細步驟 2021-10-31
- Abbiotec代理的產品得到重複驗證2020 2021-10-31
- click chemistry tools數據結果比... 2021-10-31
- LaysanBio代理商相關文獻資料2020 2021-10-31
- zyagen Laboratories代理的產品得到... 2021-06-20
- Toxin Technologies代理商相關文獻資... 2021-03-14
- 熱烈祝賀91麻豆福利视频网生物正式代理biocolor公司試劑產品... 2021-03-14
- 熱烈祝賀91麻豆福利视频网生物正式代理cytognos公司試劑產品... 2021-03-14
- Gelest代理的產品得到重複驗證2020 2021-03-14
