產品詳情
簡單介紹:
Anti-FRAT1 antibody (C-Term) (STJ118533)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FRAT1 (C-Term) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FRAT1 |
Gene ID: | 10023 |
Uniprot ID: | FRAT1_HUMAN |
Immunogen Region: | C-Term |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2). |
Immunogen Sequence: | HRLLQQLVLSGNLIKEAVRR LHSRRLQLRAKLPQRPLLGP LSAPVHEPPSPRSPRAACSD PGASGRAQLRTGDGVLVPGS |
Post Translational Modifications | Phosphorylated. |
Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. |
Protein Name | Proto-Oncogene Frat1 Frequently Rearranged In Advanced T-Cell Lymphomas 1 Frat-1 |
Database Links | Reactome: R-HSA-196299 Reactome: R-HSA-4641262 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Proto-Oncogene Frat1 antibody Anti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibody Anti-Frat-1 antibody Anti-FRAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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