產品詳情
簡單介紹:
Anti-FRK antibody (2-300 aa) [1A8H2C12] (STJ98353)
詳情介紹:
Host: | Mouse |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Tyrosine-protein kinase FRK (2-300 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Monoclonal |
Clone ID: | 1A8H2C12 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC 1:200-1:1000 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FRK |
Gene ID: | 2444 |
Uniprot ID: | FRK_HUMAN |
Immunogen Region: | 2-300 aa |
Specificity: | Rak Monoclonal Antibody detects endogenous levels of Rak protein. |
Immunogen: | Purified recombinant fragment of Rak (aa2-300) expressed in E. Coli. |
Function | Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. |
Protein Name | Tyrosine-Protein Kinase Frk Fyn-Related Kinase Nuclear Tyrosine Protein Kinase Rak Protein-Tyrosine Kinase 5 |
Database Links | Reactome: R-HSA-6798695 Reactome: R-HSA-8948751 |
Cellular Localisation | Cytoplasm Nucleus Predominantly Found In The Nucleus With A Small Fraction Found In The Cell Periphery |
Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Frk antibody Anti-Fyn-Related Kinase antibody Anti-Nuclear Tyrosine Protein Kinase Rak antibody Anti-Protein-Tyrosine Kinase 5 antibody Anti-FRK antibody Anti-PTK5 antibody Anti-RAK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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