產品詳情
簡單介紹:
Anti-CD54/Icam1 antibody [YN1/1.7.4] {PE/Cyanine7} (STJA0001311)
詳情介紹:
Host: | Rat |
Applications: | FC |
Reactivity: | Mouse |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Rat monoclonal antibody anti-Intercellular adhesion molecule 1 is suitable for use in Flow Cytometry research applications. |
Clonality: | Monoclonal |
Clone ID: | YN1/1.7.4 |
Conjugation: | PE/Cyanine7 |
Isotype: | IgG2bk |
Formulation: | PBS with 0.05% Proclin300, 1% BSA |
Concentration: | 0.2 mg/mL |
Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Gene Symbol: | Icam1 |
Gene ID: | 15894 |
Uniprot ID: | ICAM1_MOUSE |
Tissue Specificity | Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells. |
Post Translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
Protein Name | Intercellular Adhesion Molecule 1 Icam-1 Mala-2 Myd10 Cd Antigen Cd54 |
Database Links | Reactome: R-MMU-198933 Reactome: -MMU-216083 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 1 antibody Anti-Icam-1 antibody Anti-Mala-2 antibody Anti-Myd10 antibody Anti-Cd Antigen Cd54 antibody Anti-Icam1 antibody Anti-Icam-1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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