產品詳情
簡單介紹:
Anti-FBN2 antibody (STJA0008297)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Fibrillin-2 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FBN2 |
Gene ID: | 2201 |
Uniprot ID: | FBN2_HUMAN |
Specificity: | This antibody detects endogenous levels of fibrillin 2 at Human, Mouse |
Immunogen: | Synthesized peptide derived from human fibrillin 2 |
Post Translational Modifications | Placensin: N-glycosylated. O-glycosylated on serine residues by POGLUT2 and POGLUT3. |
Function | Fibrillin-2: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Placensin: Hormone secreted by trophoblasts that promotes trophoblast invasiveness. Has glucogenic activity: is able to increase plasma glucose levels. |
Protein Name | Fibrillin-2 Cleaved Into - Placensin |
Database Links | Reactome: R-HSA-1474228 Reactome: R-HSA-1566948 Reactome: R-HSA-2129379 |
Cellular Localisation | Secreted Fibrillin-2 And Placensin Chains Are Still Linked Together During The Secretion From Cells But Are Subsequently Separated By Furin Fibrillin-2: Secreted Extracellular Space Extracellular Matrix Placensin: Secreted Secreted By Placental Cells |
Alternative Antibody Names | Anti-Fibrillin-2 Cleaved Into - Placensin antibody Anti-FBN2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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