產品詳情
簡單介紹：
Anti-FBP1 antibody (239-338) [S2MR] (STJ11101382)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-FBP1 (239-338) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S2MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FBP1 |
| Gene ID: | 2203 |
| Uniprot ID: | F16P1_HUMAN |
| Immunogen Region: | 239-338 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 239-338 of human FBP1 (P09467). |
| Immunogen Sequence: | APYGARYVGSMVADVHRTLV YGGIFLYPANKKSPNGKLRL LYECNPMAYVMEKAGGMATT GKEAVLDVIPTDIHQRAPVI LGSPDDVLEFLKVYEKHSAQ |
| Tissue Specificity | Expressed in pancreatic islets. |
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity.increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. |
| Protein Name | Fructose-1 -6-Bisphosphatase 1 Fbpase 1 D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 Liver Fbpase |
| Database Links | Reactome: R-HSA-70263 |
| Alternative Antibody Names | Anti-Fructose-1 -6-Bisphosphatase 1 antibody Anti-Fbpase 1 antibody Anti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 antibody Anti-Liver Fbpase antibody Anti-FBP1 antibody Anti-FBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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