產品詳情
簡單介紹：
Anti-FDX1 antibody (61-160) (STJ11105473)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Adrenodoxin-Mitochondrial (61-160) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FDX1 |
| Gene ID: | 2230 |
| Uniprot ID: | ADX_HUMAN |
| Immunogen Region: | 61-160 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 61-160 of human FDX1 (NP_004100.1). |
| Immunogen Sequence: | SSSEDKITVHFINRDGETLT TKGKVGDSLLDVVVENNLDI DGFGACEGTLACSTCHLIFE DHIYEKLDAITDEENDMLDL AYGLTDRSRLGCQICLTKSM |
| Tissue Specificity | Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level). |
| Function | Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
| Protein Name | Adrenodoxin - Mitochondrial Adrenal Ferredoxin Ferredoxin-1 Hepatoredoxin |
| Database Links | Reactome: R-HSA-1362409 Reactome: R-HSA-196108 Reactome: R-HSA-211976 Reactome: R-HSA-2395516 Reactome: R-HSA-5579026 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Adrenodoxin - Mitochondrial antibody Anti-Adrenal Ferredoxin antibody Anti-Ferredoxin-1 antibody Anti-Hepatoredoxin antibody Anti-FDX1 antibody Anti-ADX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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