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Anti-FER antibody [5D2C4] (STJ98064) STJ98064|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：Anti-FER antibody [5D2C4] (STJ98064)

  • 產品型號：STJ98064
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
Anti-FER antibody [5D2C4] (STJ98064)
詳情介紹：
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Tyrosine-protein kinase Fer is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 5D2C4
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FER
Gene ID: 2241
Uniprot ID: FER_HUMAN
Specificity: Fer Monoclonal Antibody detects endogenous levels of Fer protein.
Immunogen: Purified recombinant fragment of human Fer expressed in E. Coli.
Post Translational Modifications Autophosphorylated. Polyubiquitinated.this leads to proteasomal degradation.
Function Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodsia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.
Protein Name Tyrosine-Protein Kinase Fer
Feline Encephalitis Virus-Related Kinase Fer
Fujinami Poultry Sarcoma/Feline Sarcoma-Related Protein Fer
Proto-Oncogene C-Fer
Tyrosine Kinase 3
P94-Fer
Database Links Reactome: R-HSA-1433557
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cell Projection
Cell Junction
Membrane
Nucleus
Cell Cortex
Associated With The Chromatin
Detected On Microtubules In Polarized And Motile Vascular Endothelial Cells
Colocalizes With F-Actin At The Cell Cortex
Colocalizes With Pecam1 And Ctnnd1 At Nascent Cell-Cell Contacts
Alternative Antibody Names Anti-Tyrosine-Protein Kinase Fer antibody
Anti-Feline Encephalitis Virus-Related Kinase Fer antibody
Anti-Fujinami Poultry Sarcoma/Feline Sarcoma-Related Protein Fer antibody
Anti-Proto-Oncogene C-Fer antibody
Anti-Tyrosine Kinase 3 antibody
Anti-P94-Fer antibody
Anti-FER antibody
Anti-TYK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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