產品詳情
簡單介紹：
Anti-CDK2AP2 antibody (51-100 aa) (STJ92755)
詳情介紹：
| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Cyclin-dependent kinase 2-associated protein 2 (51-100 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDK2AP2 |
| Gene ID: | 10263 |
| Uniprot ID: | CDKA2_HUMAN |
| Immunogen Region: | 51-100 aa |
| Specificity: | DOC-1R Polyclonal Antibody detects endogenous levels of DOC-1R protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CDKA2 at the amino acid range 51-100 |
| Post Translational Modifications | Phosphorylated by MAPK1 and CDK2. |
| Function | Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation.represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. |
| Protein Name | Cyclin-Dependent Kinase 2-Associated Protein 2 Cdk2-Associated Protein 2 Doc-1-Related Protein Doc-1r |
| Cellular Localisation | Cytoplasm Nucleus Accumulates In Immature Oocytes In The Nucleus During The First Meiotic Division Accumulates In The Cytoplasm And Localizes In Dots In The Vicinity Of The Chromosomes In A Region Enriched In Microtubules |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 2-Associated Protein 2 antibody Anti-Cdk2-Associated Protein 2 antibody Anti-Doc-1-Related Protein antibody Anti-Doc-1r antibody Anti-CDK2AP2 antibody Anti-DOC1R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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