產品詳情
簡單介紹：
Anti-SCN2B antibody (30-160) (STJ110034)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-SCN2B (30-160) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SCN2B |
| Gene ID: | 6327 |
| Uniprot ID: | SCN2B_HUMAN |
| Immunogen Region: | 30-160 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-160 of human SCN2B (NP_004579.1). |
| Immunogen Sequence: | MEVTVPATLNVLNGSDARLP CTFNSCYTVNHKQFSLNWTY QECNNCSEEMFLQFRMKIIN LKLERFQDRVEFSGNPSKYD VSVMLRNVQPEDEGIYNCYI MNPPDRHRGHGKIHLQVLME EPPERDSTVAV |
| Tissue Specificity | Brain specific. |
| Function | Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. |
| Protein Name | Sodium Channel Subunit Beta-2 |
| Database Links | Reactome: R-HSA-445095 Reactome: R-HSA-5576892 Reactome: R-HSA-9717207 |
| Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sodium Channel Subunit Beta-2 antibody Anti-SCN2B antibody Anti-UNQ326 antibody Anti-PRO386 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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