產品詳情
簡單介紹:
Anti-SULT2B1 antibody (1-365) (STJ110047)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-SULT2B1 (1-365) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:100 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SULT2B1 |
Gene ID: | 6820 |
Uniprot ID: | ST2B1_HUMAN |
Immunogen Region: | 1-365 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human SULT2B1 (NP_814444.1). |
Immunogen Sequence: | MDGPAEPQIPGLWDTYEDDI SEISQKLPGEYFRYKGVPFP VGLYSLESISLAENTQDVRD DDIFIITYPKSGTTWMIEII CLILKEGDPSWIRSVPIWER APWCETIVGAFSLPDQYSPR LMSSHLPIQIFTKAFFSSKA KVIYMGRNPRDVVVSLYHYS KIAGQLKDPGTPDQFLRDFL KGEVQFGSWFDHIKGWLRMK GKDNFLFITYEELQQDLQGS VERICGFLGRPLGKEALGS |
Tissue Specificity | Expressed in the stratum granulosum-stratum corneum junction in the skin (at protein level). Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. |
Post Translational Modifications | Phosphorylated. |
Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it has also significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation. Isoform 2: Sulfonates pregnenolone but not cholesterol. |
Protein Name | Sulfotransferase 2b1 Alcohol Sulfotransferase Hydroxysteroid Sulfotransferase 2 Sulfotransferase Family 2b Member 1 Sulfotransferase Family Cytosolic 2b Member 1 St2b1 |
Database Links | Reactome: R-HSA-156584 |
Cellular Localisation | Cytoplasm Cytosol Microsome Nucleus Phosphorylation Of Ser-348 Is Required For Translocations To The Nucleus |
Alternative Antibody Names | Anti-Sulfotransferase 2b1 antibody Anti-Alcohol Sulfotransferase antibody Anti-Hydroxysteroid Sulfotransferase 2 antibody Anti-Sulfotransferase Family 2b Member 1 antibody Anti-Sulfotransferase Family Cytosolic 2b Member 1 antibody Anti-St2b1 antibody Anti-SULT2B1 antibody Anti-HSST2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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